Peptides

MOTS-C 10 MG

$60.00

MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the mitochondrial 12S rRNA region. As a member of the small open-reading-frame peptide class, it is studied as a putative regulator of cellular energy metabolism, with reported associations to the AMP-activated protein kinase (AMPK) signaling axis and nuclear-cytoplasmic localization under metabolic stress. Its structure and proposed mechanism make it a frequent reference compound in mitochondrial and metabolic-signaling literature. In laboratory settings, researchers study MOTS-c in cultured cell lines and preclinical models to characterize its effects on glucose handling, fatty-acid metabolism, AMPK activation, and gene-expression patterns linked to metabolic homeostasis. In-vitro work also examines its translocation to the nucleus during metabolic perturbation and its interactions with stress-response pathways. These investigations are exploratory and aimed at understanding mitochondrial-nuclear communication, not at any human or veterinary application. Peptiva Research Labs supplies it as a research-grade reference compound, HPLC-verified with a COA available. For Research Use Only, not for human or veterinary use.

Read the research guide: MOTS-c (Mitochondrial-Derived Peptide): Research Overview →

Frequently asked questions

What is MOTS-c?
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded in the mitochondrial 12S rRNA region. It is studied as a putative signaling molecule involved in cellular energy metabolism. It is offered strictly as a research reference compound.
What do laboratories study MOTS-c for?
Researchers use it in cultured cells and preclinical models to examine AMPK signaling, glucose and fatty-acid metabolism, and nuclear translocation under metabolic stress. The aim is to characterize mitochondrial-nuclear communication. All such work is in-vitro or preclinical.
How is MOTS-c stored and reconstituted in the lab?
Lyophilized peptide is typically kept desiccated at -20°C and protected from light to preserve integrity. For experimental use it is commonly reconstituted in sterile or bacteriostatic water, then aliquoted to limit freeze-thaw cycles. Reconstitution protocols should follow the receiving laboratory's standards.

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